He did excellent work, and the world is a bit dimmer for his absence.
He is probably most well known for his work with Type 1 Diabetes treatment and looking at hyperglycemia as the major cause of diabetic complications. He was a pioneer in pushing for tight blood glucose control in T1Ds.
TLDR: People don't need carbohydrates, ketosis isn't dangerous.
It is pertinent to briefly discuss the enduring misconception that glucose itself represents an “absolutely essential”, “universal fuel” in human physiology, which requires nuanced definition and gradation, but has been perpetuated verbatim and may have been incorporated into the physiology education of currently practicing healthcare professionals [1-7].
We must first address the distinction between endogenous and exogenous sources of glucose. Clinical trials and epidemiological studies of very low to zero carbohydrate diets support the statement of the US National Academies of Sciences that “the lower limit of dietary carbohydrate compatible with life apparently is zero, provided that adequate amounts of protein and fat are consumed” [8-11]. Even so, despite seemingly safe and increasingly popular, the long-term effects of a truly “zero” carbohydrate diet (without micronutrient supplementation) are difficult to as
Every recipe here is crafted with purpose—nutrient-dense, blood sugar-friendly, and free from processed ingredients. Whether you’re managing diabetes or just eating for better health, these meals make it easy to stay on track without sacrificing flavor.
TLDR - If you are a ketogenic lean mass hyper responder with high LDL, insist on imaging to determine your atherosclerotic risk, as this study indicates the LDL and ApoB by itself doesn't indicate a growth in plaque.
Background - Changes in low-density lipoprotein cholesterol (LDL-C) among people following a ketogenic diet (KD) are heterogeneous. Prior work has identified an inverse association between body mass index and change in LDL-C. However, the cardiovascular disease risk implications of these lipid changes remain unknown.
Objectives - The aim of the study was to examine the association between plaque progression and its predicting factors.
Methods - One hundred individuals exhibiting KD-induced LDL-C ≥190 mg/dL, high-density lipoprotein cholesterol ≥60 mg/dL, and triglycerides ≤80 mg/dL were followed for 1 year using coronary artery calcium and coronary computed tomography angiography. Plaque progression predictors were assessed with linear regression and Bayes factors. Die
In this episode of the KetoPro Podcast, Richard Smith welcomes back Professor Tim Noakes to discuss the impact of low carbohydrate diets on athletic performance. They explore recent research findings that challenge traditional beliefs about carbohydrates and muscle glycogen, emphasizing the importance of blood glucose levels during endurance activities. The conversation also addresses the adaptation process for athletes transitioning to low carb diets, the health implications of dietary choices for athletes, and the evolving landscape of sports nutrition. In this conversation, the speakers delve into the implications of carbohydrate consumption on athletic performance and overall health. They discuss the hidden dangers of high carbohydrate diets, the efficiency of fat as a fuel source, and the body's macronutrient needs. Personal experiences with zero carb diets are shared, along with insights into the future of research in this area. The conversation also touches on the addic
Thomas N. Seyfried received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He did his undergraduate work at the University of New England, where he recently received the distinguished Alumni Achievement Award. He also holds a Master’s degree in Genetics from Illinois State University. Thomas Seyfried served with distinction in the United States Army’s First Cavalry Division during the Vietnam War and received numerous medals and commendations. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine and then served on the faculty as an Assistant Professor in Neurology.
Other awards and honours have come from such diverse organisations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, the Ketogenic Diet Special Interest Group of the American Epilepsy Society, the Academy of Comprehensive and Complementary Medicine, and the American Col
Dr Penny Figtree graduated from the University of Sydney in 1993 with first class honours. With over 20 years in general practice she has now decided to focus on weight loss and diabetes.
This decision was made after seeing the power of a low carbohydrate diet to help people lose weight and for some to even reverse diabetes. Dr Figtree had previously tried to help patients using various diets such as low fat diets, Optifast, the 5:2 fast but nothing really worked. In the end she would just say “as long as you are not gaining weight then that’s great”. Then Dr. Figtree read a book called “Always Hungry” By Professor David Ludwig where he explained the INSULIN CARBOHYDRATE MODEL OF OBESITY.
Dr. Figtree has now been practising low carb medicine for several years. She describes this as the most rewarding part of her career, stopping medications and patients feeling well.
Summarizer
Dr. Penny Figtree discusses the use of continuous glucose monitors (CGMs) in healthy individuals, em
This is IMO the most authentic flavorful enchiladas on a keto diet with my game-changing tortilla recipe! This low-carb, high-fat tortilla is not only perfect for keto enthusiasts but also a great fit for carnivore diets. In this video, we'll show you how to make the perfect keto tortilla from scratch, using two ingredients and easy-to-follow instructions. Whether you're a keto newbie or a seasoned pro, this recipe is a must-try for anyone looking to elevate their keto meal game. So, what are you waiting for? Let's get started and make some amazing keto enchiladas!
A accessible conversation on the topic of blood glucose control. Nothing ground breaking here, but a good introduction spoken in plain language going over the papers we have already reviewed.
Summarizer:
Dr. Ford Brewer discusses a step-by-step guide to reversing type 2 diabetes, emphasizing diet and lifestyle changes. He explains how carbohydrates can become detrimental as insulin sensitivity decreases with age and how proper dietary choices can significantly impact blood sugar levels. The conversation also touches on the importance of exercise, particularly muscle-building activities, and the physiological effects of fasting and body composition on diabetes management.
Key Points
Carbohydrates as a Risk Factor
Carbohydrates are not inherently toxic but can become harmful as insulin sensitivity decreases with age. Elevated blood sugar and insulin levels are linked to inflammation and vascular damage.
TLDR: Keto is good for you, and not bad for you. Despite what some agenda based people say the evidence is in favor of keto as good for you, yes even you.
As the prevalence of chronic diseases persists at epidemic proportions, health practitioners face ongoing challenges in providing effective lifestyle treatments for their patients. Even for those patients on GLP-1 agonists, nutrition counseling remains a crucial strategy for managing these conditions over the long term. This paper aims to address the concerns of patients and practitioners who are interested in a low-carbohydrate or ketogenic diet, but who have concerns about its efficacy, safety, and long-term viability. The authors of this paper are practitioners who have used this approach and researchers engaged in its study. The paper reflects our opinion and is not meant to review low-carbohydrate diets systematically. In addressing common concerns, we hope to show that this approach has been well researched and can no longer
Recently we reported similar performances in both progressive tests to exhaustion (VO2max) and 5km running time trials (5KTT) after consuming low-carbohydrate, high-fat (LCHF) or high-carbohydrate, low-fat (HCLF) diets. Accordingly, we tested the null hypothesis that the metabolic responses during both tests would be similar across diets. In a randomized, counterbalanced, cross-over design, seven male athletes (VO2max: 61.9 ± 6.1 mL/kg/min; age: 35.6 ± 8.4 years; height: 178.7 ± 4.1 cm; mass: 68.6 ± 1.6 kg; body fat: 5.0 ± 1.3%) completed six weeks of LCHF (6/69/25% energy carbohydrate/fat/protein) and HCLF (57/28/15% energy carbohydrate/fat/protein) diets, separated by a two-week washout. Substrate utilization and energy expenditure were measured during VO2max tests and 5KTTs. The LCHF diet markedly increased fat oxidation and reduced carbohydrate oxidation, with no associated impairment in either the VO2max tests or the 5KTTs. Following the LCHF diet, athletes generated 50% or more
Compared to highly trained ultra-endurance athletes consuming an HC diet, long-term keto-adaptation results in extraordinarily high rates of fat oxidation, whereas muscle glycogen utilization and repletion patterns during and after a 3 hour run are similar.
Many successful ultra-endurance athletes have switched from a high-carbohydrate to a low-carbohydrate diet, but they have not previously been studied to determine the extent of metabolic adaptations.
Twenty elite ultra-marathoners and ironman distance triathletes performed a maximal graded exercise test and a 180 min submaximal run at 64% VO2max on a treadmill to determine metabolic responses. One group habitually consumed a traditional high-carbohydrate (HC: n = 10, %carbohydrate:protein:fat = 59:14:25) diet, and the other a low-carbohydrate (LC; n = 10, 10:19:70) diet for an average of 20 months (range 9 to 36 months).
Peak fat oxidation was 2.3-fold higher in the LC group (1.54 ± 0.18 vs 0.67 ± 0.14 g/min; P = 0.000) and
TLDR: The take away from this paper is after a 6 week adaption phase a keto athlete had a higher time to exhaustion then a high carb athlete even with carb loading.
Very-low-carbohydrate diets (LCHF; <50 g/day) have been debated for their potential to lower pre-exercise muscle and liver glycogen stores and metabolic efficiency, risking premature fatigue. It is also hypothesized that carbohydrate ingestion during prolonged exercise delays fatigue by increasing carbohydrate oxidation, thereby sparing muscle glycogen. Leveraging a randomized crossover design, we evaluated performance during strenuous time-to-exhaustion (70% V̇o2max) tests in trained triathletes following 6-wk high-carbohydrate (HCLF, 380 g/day) or very-low-carbohydrate (LCHF, 40 g/day) diets to determine 1) if adoption of the LCHF diet impairs time-to-exhaustion performance, 2) whether carbohydrate ingestion (10 g/h) 6–12× lower than current CHO fueling recommendations during low glycogen availability (>15-h pre-exerci
So many of our beloved Seniors could drastically improve their health and return to productive life with a few simple changes in diet and lifestyle. We go over what it takes to optimize Senior health in this video. Elderly folks have so much wisdom and love to share with their family, but they can't do it if they are stuck in a dark nursing home, taking 20 medications a day and eating a junk diet...
Summary:
Hal Cranmer currently owns and operates four assisted living homes in very unique ways. He doesn't believe in warehousing our elderly until they die...
website: aparadiseforparents.com/assisted-living
Main Topic: Improving the health of elderly individuals to enable them to return to independent living, focusing on diet and lifestyle changes as alternatives to nursing homes.
Key Points:
Many elderly individuals in assisted living or nursing homes could significantly improve their health and return home with simple changes in diet and lifestyle.
Not all medical research is created equal, so how do we know which studies to trust?
The phrase evidence-based medicine (EBM) is often misunderstood and misused. What does it truly mean to rely on evidence in clinical decision-making?
Dr. Gordon Guyatt, the father of the term evidence-based medicine, explains how to assess scientific studies, understand the strength of different types of evidence, and apply findings to clinical decisions.
Want to make better-informed health decisions? This interview will help you learn how to critically assess medical evidence for yourself. In this conversation, Dr. Guyatt breaks down:
✅ Why some studies are more trustworthy than others\
✅ The limitations of observational studies in nutrition and medicine\
✅ How the GRADE framework categorizes evidence from high to low certainty\
✅ How to critically assess nutrition and mental health research\
✅ The importance of patient values in clinical decision-making
Aims: This study assessed the five-year effects of a continuous care intervention (CCI) delivered via telemedicine, counseling people with type 2 diabetes (T2D) on a very low carbohydrate diet with nutritional ketosis.
Results: Twenty percent (n = 24) of the five-year completers achieved remission, with sustained remission observed over three years in 15.8 % (n = 19) and four years in 12.5 % (n = 15). Reversal to HbA1c < 6.5 % without medication or only metformin was seen in 32.5 % (n = 39). Sustained improvements were noted in body mass (-7.6 %), HbA1c (-0.3 %), triglycerides (-18.4 %), HDL-C (+17.4 %), and inflammatory markers, with no significant changes in LDL-C and total cholesterol.
Conclusions: Over five years, the very low carbohydrate intervention showed excellent retention and significant health benefits, including diabetes remission, weight loss, and improved cardiometabolic markers.
Robert Lustig is a Professor of Paediatric Endocrinology and a public health expert on the impact of sugar on our health. He is the author of bestselling books such as, ‘Fat Chance’, ‘Metabolical’, and ‘The Hacking of the American Mind’.
Peter Brukner OAM, MBBS, FACSP, FACSM, FASMF, FFSEM is a specialist sports and exercise physician and the founding partner at the Olympic Park Sports Medicine Centre in Melbourne. Peter is a world renowned sports medicine clinician and researcher. His most recent team appointments have been as Head of Sports Medicine and Sports Science at Liverpool Football Club and, until 2017, Team Doctor for the Australian cricket team.
Peter is Professor of Sports Medicine at the La Trobe Sport & Exercise Medicine Research Centre at La Trobe University, Melbourne. Peter has published widely internationally with a number of books, book chapters and over 100 original research articles. He is the co-author of Clinical Sports Medicine, a best selling general sports medicine text in its fifth edition as well as Stress Fractures, Food for Sport, Encyclopedia of Exercise and Sport Health and Clinical Sports Anatomy.
Prof. Brukner is the founder of the public health campaign SugarByHalf and is committed