Research in mice suggests headache medications may reduce pain, other symptoms of the gynecologic disorder

The study, conducted in mice and led by scientists at Boston Children’s Hospital and Harvard Medical School, uncovered molecular details of how the nervous system and the immune system communicate in endometriosis.

Specifically, the researchers identified a small molecule called calcitonin gene-related peptide (CGRP) that plays an important role in this crosstalk.

The CGRP pathway is a target of several existing migraine medications, and when the team administered these drugs to lab mice, they seemed to reduce endometriosis pain and lesion size.

The researchers are now exploring partnerships with pharmaceutical companies, with the goal of launching a clinical trial to test the migraine drugs in patients with endometriosis.

A woman has a lot to think about when she is pregnant. Women who are pregnant should take care of their teeth, for themselves and their kids. Most regular dental care is safe to do while pregnant, but you should avoid certain medicines and procedures for the first three months. Let your dentist know if you are expecting.

Take care of your teeth when you have morning sickness. Some pregnant women have morning sickness, which can include vomiting or acid reflux. Tooth erosion is more likely to happen when you vomit or have acid reflux, but there are a few things you can do to lower the risk. When you get over morning sickness, make sure you brush your teeth well. If you’re not at home and don’t have your toothbrush with you, rinse your mouth out with water right away or chew sugar-free gum. You can brush your teeth when you get home. Make sure your teeth and gums are healthy. Gum disease can hurt both you and your baby’s health. Poor tooth health in mothers has been linked to kids being

Is it safe to wash your anus with water and your (ungloved) hand after pooping, assuming (of course) that you don't touch anything with your hand until you wash it with soap and water?

I'm currently traveling in India. It's common here, instead of using toilet paper after deification, to pour water down your back and use your left hand to wipe your anus clean of feces. I googled to find information from medical professionals to understand if this is safe or not, but I (surprisingly) couldn't find any information on the Internet about this.

Of course, let's assume that we're doing this properly:

1. You only use one hand (typically your left hand), so feces only contaminates one hand.
2. You don't touch anything in the bathroom (eg pitcher, faucet, door knob, etc) with your soiled left hand until after you wash your hands
3. You wash your hands properly, following best-practices: using soap and water, scrubbing vigorously for at least 20 seconds.

I'm less interested in your personal

What are the differences between the different types of Alkaline Phosphatase (ALP) tests for laboratory blood work?

I went to a medical laboratory to get yearly blood work done. In addition to testing for some specific "me" things that I'm monitoring, I want to get a CMP (Comprehensive Metabolic Panel).

I'm in a foreign country where I don't really speak the language. When I said that I wanted blood work done at the lab, the agent at the front desk handed me a form with a lot of boxes to choose what I wanted to get. There is no "CMP" option, so I tried to tick the boxes for the 14 blood tests that compose a CMP, but I got stuck when I tried to check the box for the ALP (Alkaline Phosphatase) test – because there were 3 boxes:

1. Fost. Alcalina
2. Fost. Ácida Total
3. Fost. Ac. Prostatica

What are each of these, and which of these three is the "normal" ALP test that s

I've been diagnosed with a supraspinatus tendon rupture of about 1.1 x 1.2 mm on the supraspinatus tendon (posterior fibers). Roughly, how big is it in relationship with its global size? Half? 2 thirds? I'm a small guy - 1.6m tall.

Also, does the tendon recover?

I notice my arm is still a little bit anterior rotated and down a bit as well. About a year has passed.

Should I be worried with some kind of arthrosis down the line, because of the position of the humerus on the glenoid cavity?

A new study finds that getting your blood pressure taken while you’re lying down may give a more accurate reading that could show signs of heart disease risks. Even though the new study found something different, researchers agree that sitting up is still the best way to take blood pressure. Experts say that people should make it a priority to know their blood pressure numbers and act on them, because high blood pressure can make someone more likely to have dangerous heart events. New study shows that getting your blood pressure checked while you’re lying down may give more exact results.

Every time you go to the doctor, your blood pressure is taken for a reason. Blood pressure is often a good indicator of serious health problems, like the chance of stroke, heart disease, and even dying too soon.

So, it’s important to get the most exact reading of your blood pressure so you can take care of your health.

The American Heart Association (AHA) gave a talk earlier this month about how a

CRAB is the name of a type of bacteria that can cause dangerous infections in the blood, lungs, and urinary tract, according to the U.S. Centres for Disease Control and Prevention. A group of strong medicines called carbapenems can’t kill it, which is a bad thing.

Researchers from Harvard University and the drug company Hoffmann-La Roche found that zosurabalpin, a new type of antibiotic, can kill A. baumannii in a study that came out on January 3 in the journal Nature.

Dr. Kenneth Bradley, global head of infectious disease discovery at Roche Pharma Research and Early Development and researcher, told CNN that Zosurabalpin works in a way that isn’t like anything else on the market.

His explanation was that this was a new way to do things, both in terms of the compound itself and the way it kills germs. It is hard to fight A. baumannii because it is a Gram-negative bacteria, which means it has protective membranes on both the inside and the outside.

Scientists first tried to find a mo

cross-posted from: https://midwest.social/post/6252553

Dec 7 (Reuters) - The Biden Administration on Thursday announced it is setting new policy that will allow it to seize patents for medicines developed with government funding if it believes their prices are too high.

The policy creates a roadmap for the government's so-called march-in rights, which have never been used before. They would allow the government to grant additional licenses to third parties for products developed using federal funds if the original patent holder does not make them available to the public on reasonable terms.

White House advisers said on a press call that cost to consumers is a factor government agencies may consider when thinking of using march-in rights.

*"We'll make it clear that when drug companies won't sell taxpayer funded drugs at reasonable prices, we will be prepared to allow other companies to provide those drugs for less," White House adviser Lael Brainard said

“We’ve found that antioxidants activate a mechanism that causes cancer tumors to form new blood vessels, which is surprising since it was previously thought that antioxidants have a protective effect,” said Martin Bergö, a new study’s author. “The new blood vessels nourish the tumors and can help them grow and spread.” It's worth noting that there's no harm in consuming normal antioxidant-rich foods in normal quantities, though.

Over the past several years, increasingly destructive hurricanes, wildfires, blizzards, and other extreme weather events have made it clear that the effects of climate change aren’t some future hypothetical, but our current reality. Not to be outdone, the summer of 2023 has been coming in hot — literally — with July shattering the record for the planet’s hottest month, and coming to a close with “numerous fires” breaking out in the Arctic circle. And while the recent high temperatures and debilitating humidity may not be responsible for as much property damage as a hurricane, it’s been disastrous for our mental health.

Diabetes cases are likely to skyrocket over the next few decades, new research out this week has found. The study estimates that more than a billion people worldwide will be living with the chronic condition by 2050—roughly double the amount of cases seen today. The prevalence of diabetes is expected to be especially high in parts of Africa and the Middle East, but dozens of countries could experience substantial increases.

Mental Health Apps Are a Privacy Nightmare

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In the simplest terms, diabetes is defined as having chronically high levels of blood sugar. This usually happens due to a breakdown in our production of or response to insulin, a hormone that helps move sugar from the bloodstream to our cells. People with type 1 diabetes, for instance, have an overzealous immune system that attacks the cells responsible for making insulin. And those with type 2 diabetes develop a resistance to insulin’s effects and can eventually stop producing it altogether.

Thanks

What a surprise. /j

Well, guess I'm screwed since I bump my head, semicommonly…

Also, this is NPR, so it's unsurprising they whitewashed the U.S military.

Through its savvy but legal exploitation of the U.S. patent system, Humira’s manufacturer, AbbVie, blocked competitors from entering the market. For the next six years, the drug’s price kept rising. Today, Humira is the most lucrative franchise in pharmaceutical history. AbbVie orchestrated the delay by building a formidable wall of intellectual property protection and suing would-be competitors before settling with them to delay their product launches until this year. Over the past 20 years, AbbVie and its former parent company increased Humira’s price about 30 times, most recently by 8 percent this month. Since the end of 2016, the drug’s list price has gone up 60 percent to over $80,000 a year, according to SSR Health, a research firm. AbbVie did not invent these patent-prolonging strategies; companies like Bristol Myers Squibb and AstraZeneca have deployed similar tactics to maximize profits on drugs for the treatment of cancer, anxiety and heartburn. But AbbVie’s succes